Glimepiride Dosage, Side Effects
Glimepiride dosage, side effects:
Generic Name: Glimepiride
Drug Class: Sulfonylurea (antidiabetic medication)
Brand Names
Glimepiride is sold under various brand names worldwide, including:
United States & Canada
- Amaryl (original brand by Sanofi)
- Glimepiride (generic versions)
Europe
- Amaryl (most common)
- Solosa (in some countries)
- Glimy (Italy)
- Oziclide (Spain)
India & Asia
- Amaryl
- Glimestar (Sun Pharma)
- Glynase (USV)
- Glimy (Torrent)
- Glimisave (Zydus)
Other Regions
- Amaryl (Australia, Latin America)
- Diaprel (some Middle Eastern countries)
Indications
- Type 2 Diabetes Mellitus (as an adjunct to diet and exercise)
Mechanism of Action
- Stimulates insulin release from pancreatic beta cells
- Increases tissue sensitivity to insulin
Dosage Forms
- Tablets: 1 mg, 2 mg, 3 mg, 4 mg, 6 mg, 8 mg
Side Effects
- Hypoglycemia (most common)
- Weight gain
- Dizziness
- Nausea
- Skin rash
Contraindications
- Type 1 Diabetes
- Diabetic ketoacidosis
- Severe kidney/liver disease
- Allergy to sulfonylureas
Drug Interactions
- Beta-blockers, NSAIDs, warfarin may increase hypoglycemia risk
- Alcohol increases hypoglycemia risk