Finasteride dosage, side effects
Finasteride dosage, side effects:
Finasteride is a medication primarily used to treat male pattern hair loss (androgenetic alopecia) and benign prostatic hyperplasia (BPH). It works by inhibiting the 5α-reductase enzyme, which converts testosterone into dihydrotestosterone (DHT), a hormone responsible for hair loss and prostate enlargement.
Brand Names of Finasteride
Finasteride is sold under various brand names worldwide, including:
1. For Hair Loss (1 mg dose)
- Propecia (original brand by Merck)
- Finpecia (India, Cipla)
- Fincar (India, Dr. Reddy’s)
- Finax (India, Dr. Reddy’s)
- Proscar 1 mg (some countries)
- Finasteride Generics (various manufacturers)
2. For BPH (5 mg dose)
- Proscar (original brand by Merck)
- Finast (various countries)
- Fincar 5 mg (India)
- Finasteride-5 (generic versions)
Key Facts About Finasteride
Mechanism of Action
- Blocks Type II 5α-reductase, reducing DHT levels by ~70%.
- Helps shrink the prostate (BPH) and slows hair loss.
Uses
- Male Pattern Baldness (MPB) – 1 mg/day
- Benign Prostatic Hyperplasia (BPH) – 5 mg/day
Side Effects
- Common: Decreased libido, erectile dysfunction, reduced semen volume.
- Rare: Gynecomastia (breast enlargement), depression.
- Post-Finasteride Syndrome (PFS): Controversial long-term sexual dysfunction (rare).
Contraindications
- Not for women (especially pregnant women – risk of birth defects).
- Not recommended for children.
Effectiveness
- Hair Loss: Slows balding in ~90% of men, regrows hair in ~65%.
- BPH: Reduces prostate size, improves urine flow.
Generic Availability
- Widely available as a low-cost generic drug.
Conclusion
Finasteride is a well-studied drug for hair loss and BPH, sold under brands like Propecia, Proscar, Finpecia, and Finast. While effective, it may cause sexual side effects in some men. Always consult a doctor before use.